A 10 -year -old with precocious puberty is found to have a space -occupying tumor in the arcuate nucleus of the hypothalamus, leading to excessive prolactin release. Which of the following correctly describes changes in plasma levels of hormones?

Question

Quizplus · Accepted Answer

A tumor in the arcuate nucleus of the hypothalamus leading to excessive prolactin release would likely decrease the release of prolactin-inhibiting hormone (PIH, also known as dopamine) due to the negative feedback mechanism. Prolactin-releasing hormone (PRH) levels might also decrease as the body attempts to reduce prolactin secretion. However, the tumor's direct effect on prolactin secretion overrides these regulatory mechanisms, leading to increased plasma levels of prolactin.

A 10 -Year -Old with Precocious Puberty Is Found to Have