Aspirin Is a Nonsteroidal Anti -Inflammatory Drug (NSAID) That Relieves

Aspirin is a nonsteroidal anti -inflammatory drug (NSAID) that relieves pain. Which mechanism best describes how NSAIDs work?

A) Aspirin decreases the production of thromboxane A₂, a chemical involved in blot clot formation, and COX inhibits A₂ and, therefore, blood clots do not form and cause pain.
B) Prostaglandins (PG) are eicosanoids that produce pain and inflammation. Cyclooxygenase (COX) is an essential enzyme in the production of PG and aspirin inhibits COX and therefore relieves pain due to the reduced production of PG.
C) Leukotrienes are eicosanoids that produce pain and inflammation. COX is used in the lipoxygenase pathway and therefore NSAIDs stop the conversion of arachidonic acid to leukotrienes thereby reducing inflammation.
D) When aspirin dissolves in the interstitial fluid it causes a concentration gradient and fluid is pulled from the cell reducing inflammation.
E) The COX receptors have a greater affinity for aspirin and these speed up the reactions of healing.