Doctors Often Prescribe Baby Aspirin (82 Mg) to Guard Against

Doctors often prescribe baby aspirin (82 mg) to guard against the formation of blood clots instead of a higher dose of 350 mg found in a regular aspirin. Which statement best describes the distinction in dosages?

A) Aspirin causes several side effects, some good and some bad. Aspirin decreases thromboxane A₂ which causes blood clots; however, at higher dosages, it also decreases the production of PGI₂ (prostacyclin) that inhibits production of blood clots. Thus, higher dosages of aspirin would actually promote the formation of blood clots.
B) Aspirin is an allosteric modulator that activates COX -2 in the body and it is COX -2 that primarily inhibits blood clot formation.
C) Aspirin inhibits the production of PGE₂ in the stomach, which protects the stomach lining from stomach acid causing ulcers. Lower dosages do not inhibit PGE₂ and do not harm the stomach.
D) Low dosages of aspirin inhibit a critical enzyme in the production of prostaglandins called cyclooxygenase (COX) . There are two forms of COX: 1 and 2. Low dosages enhance the production of COX -2 which reduces blood clots. COX -1 receptors only reduce pain.
E) Both dosages actually do the same thing to prevent blood clots but 82 mg of aspirin is much cheaper than 350 mg.