What molecule, whose synthesis is catalyzed by phospholipase C, triggers the release of calcium from the endoplasmic reticulum?

Question

Quizplus · Accepted Answer

Inositol triphosphate (IP3) is the molecule synthesized by the action of phospholipase C on phosphatidylinositol biphosphate (PIP2) in the plasma membrane. IP3 then diffuses through the cytoplasm to the endoplasmic reticulum, where it binds to IP3 receptors, triggering the release of calcium ions into the cytoplasm.

What Molecule, Whose Synthesis Is Catalyzed by Phospholipase C, Triggers