Peripheral chemoreceptors are specialized cells in contact with arterial blood that respond directly to changes in blood

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Peripheral chemoreceptors, such as those found in the carotid bodies and aortic bodies, respond to changes in arterial blood pH, partial pressure of oxygen (O2), and partial pressure of carbon dioxide (CO2). These changes can indicate a need for adjustments in respiration to maintain homeostasis.

Peripheral Chemoreceptors Are Specialized Cells in Contact with Arterial Blood