Which of the following statements is TRUE of communication across the neuromuscular junction?
A) Synaptic communication to the muscle cell can be excitatory or inhibitory.
B) Acetylcholine released from a motor neuron binds to muscarinic cholinergic receptors.
C) Acetylcholinesterase located in mitochondria of the motor neuron degrades acetylcholine to acetate and choline.
D) The end -plate potential is always of sufficient magnitude to depolarize the muscle cell to threshold to initiate an action potential.
E) Acetylcholinesterase located in the cytosol of the motor neuron degrades acetylcholine to acetate and choline.

Question

Quizplus · Accepted Answer

The end-plate potential at the neuromuscular junction is indeed always of sufficient magnitude to depolarize the muscle cell to threshold, thereby initiating an action potential. This ensures that once acetylcholine is released and binds to its receptors on the muscle cell, muscle contraction will follow.

Which of the Following Statements Is TRUE of Communication Across