In addition to an increase in sensitivity to glutamate, the binding of large amounts of glutamate to its receptors on the postsynaptic membrane also
A)affects other synapses that are close to the first.
B)can overwhelm the synapse.
C)stimulates the release of a paracrine messenger that further increases glutamate release.
D)directly causes more NMDA channels to open.
E)stimulates presynaptic autoreceptors and enhances its release.

Question

Quizplus · Accepted Answer

The binding of large amounts of glutamate can stimulate the release of a paracrine messenger, which can increase further glutamate release.

In Addition to an Increase in Sensitivity to Glutamate, the Binding