Substrate -level phosphorylation refers to the phosphorylation of a metabolic intermediate such as when creatine phosphate contributes a phosphate group to ADP.

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Substrate-level phosphorylation is a type of metabolic reaction where a phosphate group is directly transferred from a phosphorylated substrate to ADP, forming ATP, as seen in the example of creatine phosphate donating a phosphate group to ADP.

Substrate -Level Phosphorylation Refers to the Phosphorylation of a Metabolic