Most absorbed molecules are transported by blood to the liver prior to entering the general circulation.

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The liver acts as a primary detoxification organ and metabolizes various substances. Most nutrients absorbed in the gut enter the hepatic portal vein and are transported directly to the liver for processing before they are released into the general circulation. This process allows the liver to regulate the levels of nutrients and detoxify substances as necessary before they circulate throughout the body.

Most Absorbed Molecules Are Transported by Blood to the Liver