The most important buffer system in the extracellular fluid is

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The bicarbonate buffer system is the most important buffer system in the extracellular fluid. It helps to maintain the pH of the blood within a narrow range of 7.35-7.45. The bicarbonate buffer system consists of carbonic acid (H2CO3) and bicarbonate ion (HCO3-). When the pH of the blood decreases, carbonic acid dissociates into hydrogen ions (H+) and bicarbonate ions. The hydrogen ions are then buffered by the bicarbonate ions, which combine with them to form carbonic acid. This reaction helps to keep the pH of the blood from decreasing too much. When the pH of the blood increases, bicarbonate ions combine with hydrogen ions to form carbonic acid. This reaction helps to keep the pH of the blood from increasing too much.

The Most Important Buffer System in the Extracellular Fluid Is