If the glomerular filtration rate is 150 mL/min, renal blood flow is 750 mL/min, and the plasma concentration of solute X is 10 ng/mL, then what is the filtration fraction?
A)1500 ng/min
B)50 ng/min
C)20%
D)75 ng/min
E)10%

Question

Quizplus · Accepted Answer

The filtration fraction is calculated as the ratio of the glomerular filtration rate (GFR) to the renal plasma flow (RPF). Given that renal blood flow is 750 mL/min and assuming a hematocrit of 0.45, RPF is approximately 750 mL/min * (1 - 0.45) = 412.5 mL/min. Therefore, the filtration fraction is 150 mL/min / 412.5 mL/min = 0.3636 or 36.36%, which is closest to 20% among the given options.

If the Glomerular Filtration Rate Is 150 ML/min, Renal Blood