In diabetes mellitus, why does polyuria occur?
A)A lack of ADH decreases water reabsorption.
B)Hypoglycemia causes the excretion of a dilute urine.
C)Hyperglycemia causes some glucose to remain in the renal tubules which pulls water with it by osmosis.
D)Hyperglycemia causes increased permeability of the renal tubules to water.
E)A lack of insulin decreases water reabsorption.

Question

Quizplus · Accepted Answer

Polyuria in diabetes mellitus occurs because high blood glucose levels (hyperglycemia) exceed the renal threshold for glucose reabsorption, leading to glucose remaining in the renal tubules. This glucose acts osmotically to draw water into the urine, increasing urine volume.

In Diabetes Mellitus, Why Does Polyuria Occur