Which Statement Best Describes the Effect on the Body Due

Which statement best describes the effect on the body due to pH changes either above or below the normal range?

A) Changes in pH can denature proteins that serve as enzymes and receptors throughout the body, resulting in widespread effects on the body.
B) Changes in pH destroy the nephrons of the kidney, making kidney failure is inevitable.
C) Changes in pH out of the normal range are normal and will not have any detrimental effects on the body.
D) pH ranges vary throughout the body; therefore, blood pH has no detrimental effects on the body as it changes pH.
E) Changes in pH can only lower pH causing acidosis, meaning organs deteriorate due to high levels of acid.