Which Statement Best Describes the Bohr Effect

Which statement best describes the Bohr effect?

A) The Bohr effect refers to the release of a chemical 2,3 BPG from erythrocytes that degrades hemoglobin and releases oxygen.
B) The Bohr effect refers to the cascading events that must take place in order to chemically remove oxygen from hemoglobin.
C) The Bohr effect refers to a decrease in pH which decreases the affinity of hemoglobin for oxygen.
D) The Bohr effect speeds up metabolism and therefore increases the temperature in the body releasing oxygen to the tissues.
E) The Bohr effect refers to a decrease in carbon dioxide concentration which decreases the affinity of hemoglobin for oxygen.