Histamine induces vasodilation by stimulating the synthesis of nitric oxide.

Question

Quizplus · Accepted Answer

Histamine induces vasodilation primarily by binding to H1 receptors on endothelial cells, which leads to an increase in intracellular calcium levels and stimulates the synthesis of nitric oxide (NO). Nitric oxide is a potent vasodilator that acts on the smooth muscle cells in the vessel walls, causing them to relax and thus leading to vasodilation.

Histamine Induces Vasodilation by Stimulating the Synthesis of Nitric Oxide