When kidney biopsies from patients with Goodpasture's syndrome are stained with fluorescent antihuman globulin, bright "beads" of fluorescence can be seen scattered randomly throughout the glomeruli.

Question

Quizplus · Accepted Answer

In Goodpasture's syndrome, when kidney biopsies are stained with fluorescent antihuman globulin, the fluorescence typically outlines the glomerular basement membranes in a smooth, linear pattern rather than showing scattered "beads" of fluorescence. This linear pattern is indicative of the antibodies binding directly to the basement membrane.

When Kidney Biopsies from Patients with Goodpasture's Syndrome Are Stained