How does DNA move during gel electrophoresis?
A) Larger pieces of DNA move at a faster rate.
B) DNA moves at a constant rate, regardless of fragment size.
C) The DNA moves toward the negative electrode.
D) Smaller pieces of DNA move faster toward the positive electrode.

Question

Quizplus · Accepted Answer

DNA is negatively charged due to its phosphate backbone, so during gel electrophoresis, it moves towards the positive electrode. Smaller pieces of DNA move faster through the gel matrix than larger pieces, allowing for the separation of DNA fragments by size.

How Does DNA Move During Gel Electrophoresis