The ʺone-gene, one-enzymeʺ hypothesis concluded that
A) each allele codes for a single type of protein.
B) only certain genes function in cells.
C) specific enzymes give rise to specific genes.
D) enzymes regulate gene activity.
E) DNA is transcribed into RNA, which is translated into protein.

Question

Quizplus · Accepted Answer

The "one-gene, one-enzyme" hypothesis, proposed by George Beadle and Edward Tatum, suggests that each gene (allele) is responsible for the production of a single enzyme, which in turn affects an individual step in a metabolic pathway. This was later expanded to the "one gene, one polypeptide" concept, acknowledging that not all proteins are enzymes and that some proteins are composed of multiple polypeptides, each encoded by a separate gene.

The ʺOne-Gene, One-Enzymeʺ Hypothesis Concluded That