The DNA sequence of a portion of gene in a wild-type organism is TTACCATATTCACCC, and the corresponding peptide sequence is Leu-Pro-Tyr-Ser-Pro. The corresponding gene fragment in a phenotypic variant of the organism is TTACCATATTCACCC and the peptide sequence is Leu-Pro-Cys-Ser-Pro. This is an example of a(n) mutation (type) resulting in a
Mutation (effect).

Question

Quizplus · Accepted Answer

The mutation is a base substitution, where a single nucleotide (C) is replaced by another (T). This results in a change in the amino acid sequence of the protein, from tyrosine to cysteine. This is a missense mutation, as it changes the sense of the codon, but does not result in a stop codon.

The DNA Sequence of a Portion of Gene in a Wild-Type