Sandy Asked Professor Alperson How Decreased Volumes in Cortical Structures

Sandy asked Professor Alperson how decreased volumes in cortical structures and enlarged ventricles predispose a person to schizophrenia. Having read the recent research, Professor Alperson says, ____.

A) "They reduce dopamine activity in the brain by blocking dopamine receptor sites in post-synaptic neurons."
B) "They increase the availability of dopamine and norepinephrine in the brain and increase the severity of the symptoms."
C) "They may create subconnections between different brain regions, thereby overloading neural circuitry."
D) "They may result in weak or aberrant connections between the different brain regions, leading to reductions in the integrative function of the brain."