With regard to biomedical research, because rats, pigs, apes, and other mammals share over 90% of the same genes as humans, these animals are always good predictors for how humans will respond to a specific drug therapy.

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While rats, pigs, apes, and other mammals do share a high percentage of their genes with humans, this does not guarantee that they will always accurately predict how humans will respond to specific drug therapies. Differences in metabolism, absorption, distribution, and excretion of drugs, as well as variations in receptors and immune responses, can lead to different effects in humans compared to other animals.

With Regard to Biomedical Research, Because Rats, Pigs, Apes, and Other