Correctly order the following key steps in the process of endochondral ossification.
1)Chondrocytes die.
2)Osteoblasts build the bone collar on the external surface of the bone.
3)Perichondrium is invaded by blood vessels.
4)In the primary ossification center,osteoblasts replace calcified cartilage with early spongy bone.
5)Perichondrial cells differentiate into osteogenic cells then into osteoblasts.
A)3,5,2,1,4
B)3,1,4,5,2
C)4,3,2,1,5
D)3,1,2,3,5

Question

Correctly order the following key steps in the process of endochondral ossification. 
1)Chondrocytes die.
2)Osteoblasts build the bone collar on the external surface of the bone.
3)Perichondrium is invaded by blood vessels.
4)In the primary ossification center,osteoblasts replace calcified cartilage with early spongy bone.
5)Perichondrial cells differentiate into osteogenic cells then into osteoblasts.
A)3,5,2,1,4
B)3,1,4,5,2
C)4,3,2,1,5
D)3,1,2,3,5

Quizplus · Accepted Answer

The correct sequence for endochondral ossification starts with the invasion of the perichondrium by blood vessels (3), followed by the differentiation of perichondrial cells into osteogenic cells and then into osteoblasts (5). Next, osteoblasts build the bone collar on the external surface of the bone (2), chondrocytes die (1), and finally, in the primary ossification center, osteoblasts replace calcified cartilage with early spongy bone (4).

Correctly Order the Following Key Steps in the Process of Endochondral