Which of the following are TRUE of class I major histocompatibility complex (MHC)molecules?
A)Class I MHC molecules present exogenous antigens.
B)Class I MHC molecules are only present on erythrocyte surfaces.
C)Class I MHC molecules bind complement.
D)Class I MHC molecules present endogenous antigens.

Question

Quizplus · Accepted Answer

Class I MHC molecules present endogenous antigens. They are found on the surface of all nucleated cells in the body and present peptides derived from intracellular proteins that are produced by the cell itself. Class II MHC molecules present exogenous antigens and are found mainly on antigen-presenting cells such as dendritic cells, macrophages, and B cells. Class I MHC molecules are not present on erythrocyte surfaces, and they do not bind complement.

Which of the Following Are TRUE of Class I Major