Central chemoreceptors detect a decrease in pH in interstitial fluids in the brain.What is the response of the medulla to maintain delivery of oxygen to cells?

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The medulla responds to a decrease in pH in interstitial fluids in the brain by increasing sympathetic activity, resulting in vasoconstriction and a rise in blood pressure. This is because the increase in CO2 levels that leads to the decrease in pH triggers the medulla to increase respiratory rate, leading to an increase in oxygen delivery to cells. However, this also results in an increase in blood partial pressures of CO2 and H+, which can lead to vasodilation and a decrease in blood pressure. To counteract this, the medulla initiates a feedback loop that increases sympathetic activity, leading to vasoconstriction and a rise in blood pressure to maintain oxygen delivery to cells.

Central Chemoreceptors Detect a Decrease in PH in Interstitial Fluids