To study the influence of a single gene on behavior, researchers can render a mouse gene inactive or they can disrupt it.The results of this manipulation are called mice.

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In order to study the influence of a single gene on behavior, researchers typically use knockout mice, which have had the targeted gene rendered inactive through a genetic manipulation. This allows the researchers to investigate the effects of the missing or altered gene on the behavior of the mouse. Inbred mice are those that have been bred from closely related ancestors and have a high degree of genetic similarity, which may be useful in certain types of studies, but not necessarily in studies focusing on the effects of a single gene. Outbred mice are those that have a more diverse genetic background, and may be useful in studies where genetic variation is important. Knockin mice are those in which a new gene has been inserted into the mouse genome, and are typically used to study the function of a specific gene.

To Study the Influence of a Single Gene on Behavior