Clozapine was an improvement over previous antipsychotic medications because it

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Clozapine was the first antipsychotic medication to effectively reduce the negative symptoms of schizophrenia, such as affective flattening, social withdrawal, and lack of motivation in addition to the positive symptoms of delusions and hallucinations. It also had fewer extrapyramidal side effects such as Parkinsonian symptoms compared to previous antipsychotic medications. While it was initially used to treat schizophrenia, it has also been found to be effective in the treatment of bipolar disorder.

Clozapine Was an Improvement Over Previous Antipsychotic Medications Because It