One Negative Aspect of Using Drug Treatments for Children with Attention-Deficit/hyperactivity

One negative aspect of using drug treatments for children with attention-deficit/hyperactivity disorder is that

A) these drugs may increase the risk of later antisocial behavior.
B) the effects of these drugs are not maintained over the long term.
C) these drugs increase appetite and can lead to substantial weight gain.
D) taking these drugs as a child leads to increased risk of substance abuse as an adult.