The need to take larger and larger doses of a drug before experiencing its effects is an indication of

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Tolerance refers to the need to take larger and larger doses of a drug in order to experience its effects, as the body becomes accustomed to the presence of the drug and adapts to its effects. Withdrawal refers to physical or psychological symptoms that occur when a person stops taking a drug they have become dependent on. Psychological dependence refers to a strong desire or craving for a drug, but does not necessarily involve tolerance. Inhibition refers to the suppression or blocking of behavior.

The Need to Take Larger and Larger Doses of a Drug