The change in brain chemistry that offsets the effects of a psychoactive drug is called

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Neuroadaptation refers to the process of the brain adjusting to the presence of a psychoactive drug, which can result in the development of tolerance and withdrawal symptoms when the drug is discontinued. This process involves changes in brain chemistry that can offset the effects of the drug, leading to the need for higher doses to achieve the same effects over time. Addiction refers to a psychological and/or physical dependence on a drug, while dissociation and disinhibition are related to alterations in perception and behavior that can occur with some drugs but do not necessarily involve a change in brain chemistry.

The Change in Brain Chemistry That Offsets the Effects of a Psychoactive