Proteins that bind to DNA can either block or activate transcription.

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Proteins that bind to DNA can either block or activate transcription by binding to specific DNA sequences, such as promoters or enhancers, and regulating the recruitment or activity of RNA polymerase and other transcription factors. Some proteins act as repressors, inhibiting transcription by interfering with RNA polymerase or by recruiting histone deacetylases to condense chromatin and restrict access to DNA. Other proteins act as activators, promoting transcription by enhancing the recruitment or activity of RNA polymerase and other transcription factors, or by recruiting histone acetyltransferases to open up chromatin and facilitate access to DNA.

Proteins That Bind to DNA Can Either Block or Activate