The two- stage thymic selection process for selecting self- tolerant, antigen- reactive T cells results in

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The two-stage thymic selection process results in clonal deletion, which eliminates T cells that recognize and bind strongly to self-antigens. This process ensures that the T cells that mature and leave the thymus are self-tolerant and will not attack the body's own tissues. Somatic hypermutation, allelic exclusion, and complementarity-determining regions are not directly involved in this process.

The Two- Stage Thymic Selection Process for Selecting Self- Tolerant