T cells undergo immune selection against potential antigen- reactive cells and selection for those cells that react strongly with self- antigens.

Question

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T cells undergo processes called positive and negative selection during their development in the thymus, which helps to ensure that they can recognize and respond to foreign antigens while avoiding attacking self-antigens. Positive selection promotes the survival of T cells that can bind with moderate affinity to self-antigens presented by self-MHC molecules, while negative selection eliminates cells that bind too strongly to self-antigens, as these cells could potentially cause autoimmune diseases.

T Cells Undergo Immune Selection Against Potential Antigen- Reactive Cells