A patient who is taking dapagliflozin (Farxiga) for diabetes mellitus type 2 has also been prescribed furosemide (Lasix) for another condition. What potential risk should you monitor for on this patient?

Question

Quizplus · Accepted Answer

Dapagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor that increases urinary glucose excretion and also increases urine output. Furosemide is a loop diuretic that also increases urine output. When taken together, the risk of dehydration increases as both drugs increase urine output. Therefore, monitoring for signs and symptoms of dehydration is important in this patient.

A Patient Who Is Taking Dapagliflozin (Farxiga) for Diabetes Mellitus