Early in life, osteoblasts work faster than osteoclasts so bone is building up. At "midlife," their activity is about equal. But later on in life, the osteoclasts work faster than the osteoblasts leading to a decrease in bone mass.

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As people age, their bone mass decreases due to the osteoclasts (cells that break down bone) working faster than the osteoblasts (cells that build bone). However, in early life, osteoblasts work faster and cause bone to build up. In midlife, their activity is about equal.

Early in Life, Osteoblasts Work Faster Than Osteoclasts So Bone