A mutation that disrupts the ability of an animal cell to add polysaccharide modifications to proteins would most likely cause defects in which of the following organelles or structures?
A) nuclear matrix and extracellular matrix
B) mitochondria and Golgi apparatus
C) Golgi apparatus and extracellular matrix
D) nuclear pores and secretory vesicles

Question

Quizplus · Accepted Answer

Polysaccharide modifications of proteins occur mainly in the Golgi apparatus, which is responsible for the modification, sorting, and packaging of proteins for secretion or delivery to other organelles. The extracellular matrix is also a major site of polysaccharide modification. Therefore, a mutation that disrupts the ability of an animal cell to add polysaccharide modifications to proteins would most likely cause defects in both Golgi apparatus and extracellular matrix.

A Mutation That Disrupts the Ability of an Animal Cell