In some parts of Africa, the frequency of heterozygosity for the sickle-cell anemia allele is unusually high, presumably because this reduces the frequency of malaria. Such a relationship is related to which of the following?

Question

Quizplus · Accepted Answer

This relationship is related to Darwin's explanation of natural selection, as the allele that causes sickle-cell anemia confers some resistance to malaria, thereby increasing the fitness of individuals carrying the allele in regions where malaria is prevalent. This results in higher frequency of the allele in populations. This relationship does not involve Mendel's laws or changes in the allele due to the malarial parasite.

In Some Parts of Africa, the Frequency of Heterozygosity for the Sickle-Cell