Hutchinson-Gilford progeria is an exceedingly rare human genetic disorder in which there is very early senility and death, usually from coronary artery disease, at an average age of 13 years. Patients, who look very old even as children, do not live to reproduce. Which of the following statements represents the most likely assumption regarding this disorder?

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Quizplus · Accepted Answer

The fact that the disorder is exceedingly rare suggests that it is due to a mutation in a single gene rather than being inherited through dominant or recessive traits or increasing in frequency in successive generations within a family. Additionally, the fact that patients with the disorder do not live to reproduce suggests that it is not inherited in a simple Mendelian manner. Thus, C is the most likely assumption.

Hutchinson-Gilford Progeria Is an Exceedingly Rare Human Genetic Disorder in Which