Neuroimaging studies have shown that depression activates the left ventrolateral prefrontal cortex (VLPFC), which increases the capacity of

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Neuroimaging studies have found that the left VLPFC is activated during depressive episodes, which suggests an increase in working memory capacity. This may be due to the brain's attempt to overcome negative thoughts and emotions by keeping them in active memory, which requires increased working memory capacity. Depression does not necessarily enhance abstract reasoning or long-term memory, although it may impair both of these functions. Episodic memory may also be affected by depression, but there is insufficient evidence to suggest that it is specifically enhanced by activation of the left VLPFC.

Neuroimaging Studies Have Shown That Depression Activates the Left Ventrolateral