During meiosis, a defect occurs in a cell that results in the failure of spindle microtubules binding at the kinetochores. Which of the following statements describes the most likely result of such a defect?
A) New microtubules with more effective binding capabilities to kinetochores will be synthesized to compensate for the defect.
B) Excessive cell divisions will occur resulting in cancerous tumors and an increase in the chromosome numbers known as polyploidy.
C) The defect will be bypassed in order to ensure normal chromosome distribution in the new cells.
D) The resulting cells will not receive the correct number of chromosomes in the gametes, a condition known as aneuploidy.

Question

Quizplus · Accepted Answer

The failure of spindle microtubules to bind to kinetochores results in improper separation of chromosomes during meiosis, leading to gametes with an incorrect number of chromosomes, a condition known as aneuploidy. This can result in genetic disorders, developmental abnormalities, or even infertility. Option A is incorrect because it is unlikely that new microtubules will be synthesized to compensate for the defective ones. Option B is incorrect because excessive cell divisions will not occur as a result of this defect, and polyploidy is not a likely outcome either. Option C is incorrect because the defect cannot be bypassed, as proper attachment of spindle microtubules to kinetochores is critical for proper chromosome segregation.

During Meiosis, a Defect Occurs in a Cell That Results