The first efforts to apply scientific and systematic research methodology to establish the principle of biological determinism as the fundamental cause of criminal behavior occurred in the late nineteenth century.

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The statement is accurate. The first attempts to use scientific and systematic research methodology to establish the principle of biological determinism as the primary cause of criminal behavior began in the late 1800s. Cesare Lombroso, an Italian physician and criminologist, was one of the key proponents of this approach.

The First Efforts to Apply Scientific and Systematic Research Methodology