An epitope associates with which part of an antigen receptor or antibody?
A) the tail
B) the heavy-chain constant regions only
C) variable regions of a heavy chain and light chain combined
D) the light-chain constant regions only

Question

Quizplus · Accepted Answer

Epitopes, or antigenic determinants, are the specific parts of an antigen that are recognized and bound by the antigen receptors on lymphocytes or by antibodies. The binding occurs at the variable regions of both the heavy and light chains of the antibody or antigen receptor, where the specific shape and charge complementarity to the epitope is found. These variable regions are responsible for the specificity of antigen recognition.

An Epitope Associates with Which Part of an Antigen Receptor