How could you increase the magnitude of excitatory postsynaptic potentials (EPSPs) generated at a synapse?
A) Increase sodium-potassium pump activity.
B) Increase K⁺ permeability.
C) Increase Na⁺ permeability.
D) All of the listed responses are correct.

Question

Quizplus · Accepted Answer

Increasing Na⁺ permeability would allow more Na⁺ to flow into the postsynaptic neuron, resulting in a larger EPSP. Choices A and B would not directly affect the magnitude of EPSPs, and choice D is incorrect because increasing K⁺ permeability could actually decrease the magnitude of EPSPs by allowing more K⁺ to leave the cell and counteract the depolarizing effect of Na⁺ influx.

How Could You Increase the Magnitude of Excitatory Postsynaptic Potentials