What aspect of chromosome behaviour most clearly accounts for Mendel's law of independent assortment?
A) Movement of sister chromatids to opposite poles at anaphase II of meiosis
B) Movement of homologous chromosomes to opposite poles at anaphase I of meiosis
C) Crossing-over between homologous chromosomes during prophase I of meiosis
D) Replication of chromosomes prior to meiosis
E) Independent alignment of different homologous pairs on the metaphase I spindle
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