What Is the Relationship of Francois Jacob to Synthetic Biology

What is the relationship of Francois Jacob to synthetic biology?

A) One of his quotations was included in the watermark in the first synthetic genome.
B) His discoveries about electrical circuit engineering have been applied to genetic circuits.
C) He led the synthesis of the first synthetic genome.
D) His discoveries about gene regulation facilitated the eventual development of synthetic biology.
E) He led the sequencing of the human genome,which provided models for synthetic genes.