Alterations in the activity of cyclin-dependent kinases can affect the _____________ cell cycle checkpoint.

Question

Quizplus · Accepted Answer

Cyclin-dependent kinases (CDKs) play a critical role in regulating the cell cycle, and alterations in their activity can affect the checkpoints that occur during progression from one phase to the next. The G1/S and G2/M checkpoints are regulated by CDKs, specifically the transition from G1 to S is regulated by CDKs of the G1/S checkpoint and the transition from G2 to M is regulated by CDKs of the G2/M checkpoint. Therefore, alterations in CDK activity can affect either the G1/S checkpoint (G₁-to-S) or the G2/M checkpoint (G₂-to-M) or both (G₁-to-S or G₂-to-M). Thus, the best choice is D.

Alterations in the Activity of Cyclin-Dependent Kinases Can Affect the _____________