Frequency of disease alleles is influenced by

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Quizplus · Accepted Answer

The frequency of disease alleles is influenced by several factors including heterozygote advantage, mutation, time of onset of disease, and selection. Therefore, all of the choices are correct. Heterozygote advantage can increase the frequency of disease alleles if the heterozygous individuals have a survival advantage over the homozygotes. Mutation can introduce new disease alleles into a population. The time of onset of disease can affect the selection pressure on the allele. For example, if the disease onset occurs after the reproductive age, then natural selection may not significantly reduce the allele frequency. Selection can either increase or decrease the frequency of disease alleles in a population, depending on the consequences of the disease on survival and reproduction.

Frequency of Disease Alleles Is Influenced by