Which of the following is the correct order of decreasing leaving group ability in nucleophilic acyl substitutions (better leaving group worse leaving group)?

Question

Which of the following is the correct order of decreasing leaving group ability in nucleophilic acyl substitutions (better leaving group > worse leaving group)?

Quizplus · Accepted Answer

The leaving group ability is determined by the stability of the departing group. The more stable the anion formed after departure, the easier the departure. In this case, Cl is the best leaving group because the anion formed after the departure is stabilized by resonance. The anion formed by the departure of NHS is stabilized by a lone pair of electrons on nitrogen, but it is not as stable as the anion formed by Cl. The anion formed by the departure of CHS is not significantly stabilized, making it the worst leaving group. Therefore, the correct order is Cl > NHS > CHS. The correct order is present in option C.

Which of the Following Is the Correct Order of Decreasing