The following factor is most closely related to relapse in persons with schizophrenia.

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Lack of adherence to psychotropic medications is the most closely related factor to relapse in persons with schizophrenia. Consistent use of medication is crucial for managing symptoms and preventing relapse, but many individuals with schizophrenia struggle with adherence due to side effects, stigma, lack of insight into their illness, and other factors.

The Following Factor Is Most Closely Related to Relapse in Persons