The following is step 3 of the citric acid cycle. Isocitrate is converted into α-ketoglutarate by a(n) _______ reaction followed by _______.
A) oxidation-reduction; phosphorylation
B) phosphorylation; oxidation-reduction
C) isomerization; dehydration
D) oxidation-reduction; decarboxylation
E) hydration; decarboxylation

Question

The following is step 3 of the citric acid cycle. Isocitrate is converted into α-ketoglutarate by a(n) _______ reaction followed by _______. 
A) oxidation-reduction; phosphorylation 
B) phosphorylation; oxidation-reduction 
C) isomerization; dehydration 
D) oxidation-reduction; decarboxylation 
E) hydration; decarboxylation

Quizplus · Accepted Answer

Isocitrate is converted into α-ketoglutarate by an oxidation-reduction reaction (loss of CO2 and NADH production) followed by a decarboxylation reaction. Choice D is the only option that includes these two reactions.

The Following Is Step 3 of the Citric Acid Cycle