Which of the following statements about the classical pathway of complement activation is FALSE?
A) C1 is the first protein activated in the classical pathway.
B) The C1 protein complex is initiated by antigen-antibody complexes.
C) C3b causes opsonization.
D) Cleaved fragments of some of the proteins act to increase inflammation.
E) C3 is not involved in the classical pathway.

Question

Quizplus · Accepted Answer

C3 is indeed involved in the classical pathway; it is cleaved into C3a and C3b, which play roles in inflammation and opsonization, respectively.

Which of the Following Statements About the Classical Pathway of Complement